Tear proteomic analysis

Contact lenses (CLs) can alter the composition of tears, body fluids containing mainly water, lipids, and proteins. In particular, the ensemble of the protein expressed, defined as proteome, is highly dynamic and can be influenced by external factors, such as CL wear. In collaboration with the Centre of Optics and Optometry (COMiB) and with the Department of Biotechnology and Biosciences of the University of Milano-Bicocca (BtBs), this project is focused on the investigation of the human tear proteome of CL wearers by employing advanced mass-spectrometry based approaches. The possibility to compare differences in protein expression in different conditions could provide useful information for CL material development, as well as improvements in diagnostics and therapeutics.